Cyclin-Dependent Kinase Inhibitor p16

A product of the p16 tumor suppressor gene (GENES, P16). It is also called INK4 or INK4A because it is the prototype member of the INK4 CYCLIN-DEPENDENT KINASE INHIBITORS. This protein is produced from the alpha mRNA transcript of the p16 gene. The other gene product, produced from the alternatively spliced beta transcript, is TUMOR SUPPRESSOR PROTEIN P14ARF. Both p16 gene products have tumor suppressor functions.

Also Known As:

CDKN2 Protein; CDKN2A Protein; Cdk4-Associated Protein p16; Cyclin-Dependent Kinase Inhibitor-2A; INK4A Protein; MTS1 Protein; Multiple Tumor Suppressor-1; p16(INK4A); p16INK4 Protein; p16INK4A Protein; Cdk4 Associated Protein p16; Cyclin Dependent Kinase Inhibitor 2A; Cyclin Dependent Kinase Inhibitor p16; Multiple Tumor Suppressor 1; Protein, INK4A

Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Cell Cycle Proteins: 812
    - Cyclin-Dependent Kinase Inhibitor Proteins: 17
      - Cyclin-Dependent Kinase Inhibitor p16: 1934
  - Intracellular Signaling Peptides and Proteins: 32
    - Cyclin-Dependent Kinase Inhibitor Proteins: 17
      - Cyclin-Dependent Kinase Inhibitor p16: 1934
  - Neoplasm Proteins: 2
    - Tumor Suppressor Proteins: 1691
      - Cyclin-Dependent Kinase Inhibitor Proteins: 17
        Cyclin-Dependent Kinase Inhibitor p16: 1934
- Peptides: 84029
  - Intracellular Signaling Peptides and Proteins: 32
    - Cyclin-Dependent Kinase Inhibitor Proteins: 17
      - Cyclin-Dependent Kinase Inhibitor p16: 1934

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Disease

Drug/Important Bio-Agent (IBA)